人乳腺癌细胞SUM149
BLUEFBIO™ Product Sheet
细胞名称 |
人乳腺癌细胞SUM149 |
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货物编码 |
BFN60807665 |
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产品规格 |
T25培养瓶x1 |
1.5ml冻存管x2 |
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细胞数量 |
1x10^6 |
1x10^6 |
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保存温度 |
37℃ |
-198℃ |
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运输方式 |
常温保温运输 |
干冰运输 |
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安全等级 |
1 |
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用途限制 |
仅供科研 2类 |
培养体系 |
90%DMEM+10%FBS+1%双抗 |
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培养温度 |
37℃ |
二氧化碳浓度 |
5% |
简介 |
人乳腺癌细胞SUM149取自40岁女性 |
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注释 |
Group: Triple negative breast cancer (TNBC) cell line. Transfected with: UniProtKB; P08659; Firefly luciferase. |
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基因突变 |
Hemizygous for BRCA1 p.Asn723fs*13 (c.2169delT) (2288delT) (from parent cell line). Homozygous for CDKN2A deletion (from parent cell line). Heterozygous for EP300 c.5224+28del3 (from parent cell line). TP53 p.Met237Ile (c.711G>A) (from parent cell line). |
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HLA信息 |
/ |
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STR信息 |
/ |
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参考文献 |
PubMed=20229045; DOI=10.1007/s10585-010-9321-4 Singh B., Cook K.R., Martin C., Huang E.H., Mosalpuria K., Krishnamurthy S., Cristofanilli M., Lucci A. Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer. Clin. Exp. Metastasis 27:233-240(2010)
PubMed=25279830; DOI=10.1371/journal.pone.0109487 Singh B., Shamsnia A., Raythatha M.R., Milligan R.D., Cady A.M., Madan S., Lucci A. Highly adaptable triple-negative breast cancer cells as a functional model for testing anticancer agents. PLoS ONE 9:E109487-E109487(2014) |