人口腔舌鳞癌细胞YD-10B
BLUEFBIO™ Product Sheet
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细胞名称 |
人口腔舌鳞癌细胞YD-10B |
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货物编码 |
BFN60808627 |
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产品规格 |
T25培养瓶x1 |
1.5ml冻存管x2 |
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细胞数量 |
1x10^6 |
1x10^6 |
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保存温度 |
37℃ |
-198℃ |
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运输方式 |
常温保温运输 |
干冰运输 |
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安全等级 |
1 |
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用途限制 |
仅供科研 2类 |
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培养体系 |
DMEM高糖+10%FBS+1%三抗 |
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培养温度 |
37℃ |
二氧化碳浓度 |
5% |
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简介 |
人口腔舌鳞癌细胞YD-10B取自67岁男性供体。 |
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注释 |
Part of: Cancer Cell Line Encyclopedia (CCLE) project. Doubling time: 25.3 hours (PubMed=16264262). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. |
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基因突变 |
Heterozygous for CDKN2A p.Glu88Ter (c.262G>T) and p.Trp110Ter (c.330G>A) (p.Gly125Arg; c.373G>A) (CCLE). Homozygous for TP53 p.Tyr236Ter (c.708C>A) (PubMed=16264262; CCLE). |
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HLA信息 |
/
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STR信息 |
Amelogenin X,Y CSF1PO 12,13 D3S1358 17 D5S818 11,13 D7S820 11 D8S1179 11 D13S317 8,9 (KCLB) 9 (PubMed=16264262) D16S539 10,11 D18S51 14 D21S11 30,32 DXS101 22 FGA 23 Penta D 8,9 Penta E 5,8 TH01 6,9 TPOX 8 vWA 18,19,20 (PubMed=16264262) 18,19 (KCLB) |
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参考文献 |
PubMed=16264262; DOI=10.1038/emm.2005.48 Lee E.J., Kim J., Lee S.A., Kim E.-J., Chun Y.-C., Ryu M.H., Yook J.-I. Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells. Exp. Mol. Med. 37:379-390(2005)
PubMed=17404023; DOI=10.1196/annals.1397.014 Kwak Y.E., Jeon N.K., Kim J., Lee E.J. The cyclooxygenase-2 selective inhibitor celecoxib suppresses proliferation and invasiveness in the human oral squamous carcinoma. Ann. N. Y. Acad. Sci. 1095:99-112(2007)
PubMed=22460905; DOI=10.1038/nature11003 Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 483:603-607(2012)
PubMed=23708675; DOI=10.3892/ijo.2013.1953 Oh J.-E., Kim J.-O., Shin J.-Y., Zhang X.-H., Won H.-S., Chun S.-H., Jung C.-K., Park W.-S., Nam S.-W., Eun J.-W., Kang J.-H. Molecular genetic characterization of p53 mutated oropharyngeal squamous cell carcinoma cells transformed with human papillomavirus E6 and E7 oncogenes. Int. J. Oncol. 43:383-393(2013)
PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A. An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines. Cancer Res. 79:1263-1273(2019)
PubMed=31068700; DOI=10.1038/s41586-019-1186-3 Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature 569:503-508(2019)
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