人脐静脉内皮细胞融合细胞EA.hy926
BLUEFBIO™ Product Sheet
细胞名称 |
人脐静脉内皮细胞融合细胞EA.hy926 |
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货物编码 |
BFN60808855 |
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产品规格 |
T25培养瓶x1 |
1.5ml冻存管x2 |
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细胞数量 |
1x10^6 |
1x10^6 |
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保存温度 |
37℃ |
-198℃ |
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运输方式 |
常温保温运输 |
干冰运输 |
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安全等级 |
1 |
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用途限制 |
仅供科研 2类 |
培养体系 |
内皮细胞专用培养基 |
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培养温度 |
37℃ |
二氧化碳浓度 |
5% |
简介 |
人脐静脉内皮细胞融合细胞EA.hy926,该细胞为脐静脉内皮细胞与A549/8的融合细胞。该细胞保藏于ATCC。 |
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注释 |
Group: Space-flown cell line (cellonaut). Characteristics: Produced by the fusion of A549/8 with human umbilical vein endothelial cells. Doubling time: 12 hours (PubMed=6407019). Omics: Transcriptome analysis. Anecdotal: Have been flown in space on Shijian-10 and on the ISS in 2016 to study growth and secretion in microgravity (PubMed=28199884; PubMed=30108515; PubMed=30977987). Misspelling: EA.hy 296; Occasionally. Misspelling: EA-hy 296; Occasionally. Misspelling: EA.hy296; Occasionally. |
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基因突变 |
Homozygous for KRAS p.Gly12Ser (c.34G>A) (ClinVar=VCV000012584) (from parent cell line). Homozygous for STK11 p.Gln37Ter (c.109C>T) (ClinVar=VCV000376334) (from parent cell line). |
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HLA信息 |
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STR信息 |
Amelogenin X CSF1PO 10,11,12 D5S818 11 D7S820 8,9,10 D13S317 11 D16S539 11,12 TH01 6,8,9.3 TPOX 8,9 vWA 14,17 |
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参考文献 |
PubMed=16575254; DOI=10.1097/01.mbc.0000220237.99843.a1 Boerma M., Burton G.R., Wang J., Fink L.M., McGehee R.E. Jr., Hauer-Jensen M. Comparative expression profiling in primary and immortalized endothelial cells: changes in gene expression in response to hydroxy methylglutaryl-coenzyme A reductase inhibition. Blood Coagul. Fibrinolysis 17:173-180(2006)
PubMed=28199884; DOI=10.1016/j.biomaterials.2017.02.005 Pietsch J., Gass S., Nebuloni S., Echegoyen D., Riwaldt S., Baake C., Bauer J., Corydon T.J., Egli M., Infanger M., Grimm D. Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission -- The SPHEROIDS project. Biomaterials 124:126-156(2017)
PubMed=30108515; DOI=10.3389/fphys.2018.01025 Li N., Wang C.-Z., Sun S.-J., Zhang C., Lu D.-Y., Chen Q., Long M. Microgravity-induced alterations of inflammation-related mechanotransduction in endothelial cells on board SJ-10 satellite. Front. Physiol. 9:1025-1025(2018)
PubMed=30977987; DOI=10.33594/000000071 Kruger M., Pietsch J., Bauer J., Kopp S., Carvalho D.T.O., Baatout S., Moreels M., Melnik D., Wehland M., Egli M., Jayashree S., Kobbero S.D., Corydon T.J., Nebuloni S., Gass S., Evert M., Infanger M., Grimm D. Growth of endothelial cells in space and in simulated microgravity -- a comparison on the secretory level. Cell. Physiol. Biochem. 52:1039-1060(2019) |