人乳腺癌细胞2LMP

细胞名称

人乳腺癌细胞2LMP

货物编码

BFN60808897

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研   3类

培养体系

90%DMEM+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人乳腺癌细胞2LMP取自51岁女性乳腺癌患者胸腔积液，贴壁培养。

注释

Group: Triple negative breast cancer (TNBC) cell line.

Omics: Deep RNAseq analysis.

基因突变

Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).

Homozygous for CDKN2A deletion (from parent cell line).

Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).

TERT c.228C>T (-124C>T); in promoter (from parent cell line).

Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).

HLA信息

/

STR信息

/

参考文献

PubMed=9739048; DOI=10.1172/JCI3492

Zhai Y., Guo R., Hsu T.-L., Yu G.-L., Ni J., Kwon B.S., Jiang G.-W., Lu J., Tan J., Ugustus M., Carter K., Rojas L., Zhu F., Lincoln C., Endress G., Xing L., Wang S., Oh K.-O., Gentz R., Ruben S., Lippman M.E., Hsieh S.-L., Yang D.

LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer.

J. Clin. Invest. 102:1142-1151(1998)