人乳腺癌细胞他莫西酚耐药株LCC2

细胞名称

人乳腺癌细胞他莫西酚耐药株LCC2

货物编码

BFN60808911

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研   3类

培养体系

90%DMEM+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人乳腺癌细胞他莫西酚耐药株LCC2取自69岁女性供体，耐药倍数17。

注释

倍增时间34h

基因突变

/

HLA信息

/

STR信息

/

参考文献

PubMed=8324732

 Brunner N., Frandsen T.L., Holst-Hansen C., Bei M., Thompson E.W., Wakeling A.E., Lippman M.E., Clarke R.

 MCF7/LCC2: a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780.

 Cancer Res. 53:3229-3232(1993)

PubMed=11078910; DOI=10.1016/S0304-3835(00)00579-6

 Lilling G., Hacohen H., Nordenberg J., Livnat T., Rotter V., Sidi Y.

 Differential sensitivity of MCF-7 and LCC2 cells, to multiple growth inhibitory agents: possible relation to high bcl-2/bax ratio?

 Cancer Lett. 161:27-34(2000)

PubMed=23868472; DOI=10.1038/ncomms3175

 Johansson H.J., Sanchez B.C., Mundt F., Forshed J., Kovacs A., Panizza E., Hultin-Rosenberg L., Lundgren B., Martens U., Mathe G., Yakhini Z., Helou K., Krawiec K., Kanter L., Hjerpe A., Stal O., Linderholm B.K., Lehtio J.

 Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer.

 Nat. Commun. 4:2175-2175(2013)