人急性髓系白血病细胞MOLM-14
BLUEFBIO™ Product Sheet
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细胞名称 |
人急性髓系白血病细胞MOLM-14 |
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货物编码 |
BFN60810333 |
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产品规格 |
T25培养瓶x1 |
1.5ml冻存管x2 |
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细胞数量 |
1x10^6 |
1x10^6 |
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保存温度 |
37℃ |
-198℃ |
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运输方式 |
常温保温运输 |
干冰运输 |
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安全等级 |
1 |
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用途限制 |
仅供科研 3类 |
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培养体系 |
90%DMEM+10%FBS+1%三抗 |
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培养温度 |
37℃ |
二氧化碳浓度 |
5% |
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简介 |
人急性髓系白血病细胞MOLM-14取自20岁男性外周血，该细胞源于DSMZ |
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注释 |
Doubling time: 3-4 days (PubMed=9305600); ~50 hours (DSMZ). Omics: Deep quantitative phosphoproteome analysis. Omics: H3K79me1 ChIP-seq epigenome analysis. Derived from sampling site: Peripheral blood. |
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基因突变 |
KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) gene fusion (PubMed=9305600). FLT3 internal tandem duplication (FLT3-ITD) (PubMed=12529668). |
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HLA信息 |
/ |
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STR信息 |
Amelogenin X,Y CSF1PO 10,12 D2S1338 23,25 D3S1358 15 D5S818 10,11 D7S820 10,12 D8S1179 13,14 D13S317 10,11 D16S539 10,11 D18S51 13,15 D19S433 12,14 D21S11 30,31 FGA 21,23 TH01 7 TPOX 8 vWA 16,17 |
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参考文献 |
PubMed=9305600; DOI=10.1038/sj.leu.2400768 Matsuo Y., MacLeod R.A.F., Uphoff C.C., Drexler H.G., Nishizaki C., Katayama Y., Kimura G., Fujii N., Omoto E., Harada M., Orita K. Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23). Leukemia 11:1469-1477(1997)
DOI=10.1016/B978-0-12-221970-2.50457-5 Drexler H.G. The leukemia-lymphoma cell line factsbook. (In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)
PubMed=12529668; DOI=10.1038/sj.leu.2402740 Quentmeier H., Reinhardt J., Zaborski M., Drexler H.G. FLT3 mutations in acute myeloid leukemia cell lines. Leukemia 17:120-124(2003)
PubMed=21552520; DOI=10.1371/journal.pone.0019169 Gu T.-L., Nardone J., Wang Y., Loriaux M., Villen J., Beausoleil S., Tucker M., Kornhauser J., Ren J., MacNeill J., Gygi S.P., Druker B.J., Heinrich M.C., Rush J., Polakiewicz R.D. Survey of activated FLT3 signaling in leukemia. PLoS ONE 6:E19169-E19169(2011)
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