人乳腺癌细胞MX-1

细胞名称

人乳腺癌细胞MX-1

货物编码

BFN60810346

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研   2类

培养体系

90%DMEM(不含丙酮酸钠）+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人乳腺癌细胞MX-1取自29岁女性供体，贴壁培养，该细胞源于CLS。

注释

Part of: GrayJW breast cancer cell line panel.

Characteristics: Established from a tumor xenograft established in atyhmic mice.

Doubling time: 30-35 hours (CLS); 113.83 hours (https://www.synapse.org/#!Synapse:syn2347014).

Omics: Deep exome analysis.

Omics: Deep RNAseq analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

基因突变

/

HLA信息

Class I

HLA-A        A*11:01,74:01

HLA-B        B*35:01,15:03

HLA-C        C*04:01,02:02

Class II

HLA-DQ        DQB1*05:01,03:09

HLA-DR        DRB1*01:03,11:08

STR信息

Amelogenin        X

CSF1PO        11

D2S1338        19

D3S1358        15

D5S818        12

D7S820        11,12 (CLS)

11 (PubMed=25877200)

D8S1179        11,12,13 (CLS)

11 (PubMed=25877200)

D13S317        11,12 (CLS)

11 (PubMed=25877200)

D16S539        12

D18S51        12,16

D19S433        13,15.2,16.2

D21S11        29,30,31,32 (CLS)

29,32 (PubMed=25877200)

FGA        20

Penta D        6,9,11

Penta E        14

TH01        7,9

TPOX        7,8 (CLS)

8 (PubMed=25877200)

vWA        17,18 (CLS)

17 (PubMed=25877200)

参考文献

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110

Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y., Mills G.B., Cho R.J., Collisson E.A., van't Veer L.J., Spellman P.T., Gray J.W.

Modeling precision treatment of breast cancer.

Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893

Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.

OncoImmunology 3:E954893-E954893(2014)

PubMed=25485619; DOI=10.1038/nbt.3080

Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.

A comprehensive transcriptional portrait of human cancer cell lines.

Nat. Biotechnol. 33:306-312(2015)