人肾近端小管上皮细胞RPTEC TERT1

细胞名称

人肾近端小管上皮细胞RPTEC/TERT1

货物编码

BFN60810533

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研   2类

培养体系

DMEM高糖（不含丙酮酸钠）+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人肾近端小管上皮细胞RPTEC/TERT1取自男性成年供体。该细胞保藏于ATCC.

注释

Doubling time: ~96 hours (PubMed=18715936); 76.8 hours (PubMed=31078587).

Transfected with: HGNC; 11730; TERT.

Omics: Metabolome analysis.

基因突变

/

HLA信息

/

STR信息

Amelogenin        X,Y

CSF1PO        11

D5S818        9,11

D7S820        10

D13S317        11,13

D16S539        11,12

TH01        9,9.3

TPOX        8,11

vWA        16,18

参考文献

PubMed=18715936; DOI=10.1152/ajprenal.90405.2008

Wieser M., Stadler G., Jennings P., Streubel B., Pfaller W., Ambros P.F., Riedl C., Katinger H., Grillari J., Grillari-Voglauer R.

hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics.

Am. J. Physiol. Renal Physiol. 295:F1365-F1375(2008)

PubMed=21103459; DOI=10.1039/c0mb00146e

Ellis J.K., Athersuch T.J., Cavill R., Radford R., Slattery C., Jennings P., McMorrow T., Ryan M.P., Ebbels T.M., Keun H.C.

Metabolic response to low-level toxicant exposure in a novel renal tubule epithelial cell system.

Mol. Biosyst. 7:247-257(2011)

PubMed=25536518; DOI=10.1016/j.tiv.2014.11.015

Crean D., Bellwon P., Aschauer L., Limonciel A., Moenks K., Hewitt P.G., Schmidt T., Herrgen K., Dekant W., Lukas A., Bois F., Wilmes A., Jennings P., Leonard M.O.

Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing.

Toxicol. In Vitro 30:128-137(2015)

PubMed=31078587; DOI=10.1016/j.taap.2019.05.007

Shrestha S., Garrett S.H., Sens D.A., Zhou X.-D., Guyer R., Somji S.

Characterization and determination of cadmium resistance of CD133(+)/CD24(+) and CD133(-)/CD24(+) cells isolated from the immortalized human proximal tubule cell line, RPTEC/TERT1.

Toxicol. Appl. Pharmacol. 375:5-16(2019)