人NK T细胞淋巴瘤细胞SNK-6
BLUEFBIO™ Product Sheet
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细胞名称 |
人NK T细胞淋巴瘤细胞SNK-6 |
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货物编码 |
BFN60870138 |
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产品规格 |
T25培养瓶x1 |
1.5ml冻存管x2 |
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细胞数量 |
1x10^6 |
1x10^6 |
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保存温度 |
37℃ |
-198℃ |
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运输方式 |
常温保温运输 |
干冰运输 |
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安全等级 |
1 |
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用途限制 |
仅供科研 3类 |
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培养体系 |
DMEM高糖（HYCLONE SH30022.01)+10%FBS+1%三抗+200ug/ml IL2 |
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培养温度 |
37℃ |
二氧化碳浓度 |
5% |
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简介 |
人NK T细胞淋巴瘤细胞SNK-6取自62岁男性供体 |
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注释 |
Characteristics: IL2 dependent. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Omics: CNV analysis. Omics: Transcriptome analysis. |
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基因突变 |
/ |
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HLA信息 |
/ |
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STR信息 |
/ |
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参考文献 |
PubMed=11157488; DOI=10.1182ood.V97.3.708 Nagata H., Konno A., Kimura N., Zhang Y., Kimura M., Demachi A., Sekine T., Yamamoto K., Shimizu N. Characterization of novel natural killer (NK)-cell and gammadelta T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virus. Blood 97:708-713(2001)
PubMed=12780797; DOI=10.1046/j.1365-2141.2003.04359.x Zhang Y., Nagata H., Ikeuchi T., Mukai H., Oyoshi M.K., Demachi A., Morio T., Wakiguchi H., Kimura N., Shimizu N., Yamamoto K. Common cytological and cytogenetic features of Epstein-Barr virus (EBV)-positive natural killer (NK) cells and cell lines derived from patients with nasal T/NK-cell lymphomas, chronic active EBV infection and hydroa vacciniforme-like eruptions. Br. J. Haematol. 121:805-814(2003)
PubMed=19194464; DOI=10.1038/leu.2009.3 Iqbal J., Kucuk C., Deleeuw R.J., Srivastava G., Tam W., Geng H., Klinkebiel D., Christman J.K., Patel K., Cao K., Shen L., Dybkaer K., Tsui I.F.L., Ali H., Shimizu N., Au W.Y., Lam W.L., Chan W.C. Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. Leukemia 23:1139-1151(2009)
PubMed=21052088; DOI=10.1038/leu.2010.255 Iqbal J., Weisenburger D.D., Chowdhury A., Tsai M.Y., Srivastava G., Greiner T.C., Kucuk C., Deffenbacher K., Vose J., Smith L., Au W.Y., Nakamura S., Seto M., Delabie J., Berger F., Loong F., Ko Y.-H., Sng I., Liu X., Loughran T.P. Jr., Armitage J.O., Chan W.C. Natural killer cell lymphoma shares strikingly similar molecular features with a group of non-hepatosplenic gammadelta T-cell lymphoma and is highly sensitive to a novel aurora kinase A inhibitor in vitro. Leukemia 25:348-358(2011)
PubMed=22102884; DOI=10.1371/journal.pone.0027271 Ramakrishnan R., Donahue H., Garcia D., Tan J., Shimizu N., Rice A.P., Ling P.D. Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas. PLoS ONE 6:E27271-E27271(2011)
PubMed=25586472; DOI=10.1038/ncomms7025 Kucuk C., Jiang B., Hu X., Zhang W., Chan J.K.C., Xiao W., Lack N., Alkan C., Williams J.C., Avery K.N., Kavak P., Scuto A., Sen E., Gaulard P., Staudt L.M., Iqbal J., Zhang W., Cornish A., Gong Q., Yang Q., Sun H., d'Amore F., Leppa S., Liu W., Fu K., de Leval L., McKeithan T., Chan W.C. Activating mutations of STAT5B and STAT3 in lymphomas derived from gammadelta-T or NK cells. Nat. Commun. 6:6025-6025(2015)
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