人胃腺癌细胞SNU-1

细胞名称

人胃腺癌细胞SNU-1

货物编码

BFN6021541

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研用途        3类

培养体系

DMEM高糖培养基（不含丙酮酸钠）+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人胃腺癌细胞SNU-1取自44岁男性供体。

注释

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Part of: COSMIC cell lines project.

Part of: MD Anderson Cell Lines Project.

Part of: Seoul National University (SNU) cell line collection.

Population: Korean.

Doubling time: 26 hours (ATCC; PubMed=2158397).

Microsatellite instability: Instable (MSI-high) (PubMed=10674020; PubMed=31068700; Sanger).

Omics: Deep exome analysis.

Omics: Deep quantitative proteome analysis.

Omics: Deep RNAseq analysis.

Omics: DNA methylation analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

突变信息

Heterozygous for ATM p.Leu1154fs*12 (c.3457_3458insT) (CCLE; Cosmic-CLP).

Heterozygous for JAK1 p.Lys860Asnfs*16 (c.2580delA) (CCLE; Cosmic-CLP).

Heterozygous for KRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000012582) (PubMed=12068308; CCLE).

Mutation; TP53; none detected (PubMed=1676761).

STR信息

Amelogenin X,Y

CSF1PO 12,13 (ATCC; Cosmic-CLP)

 12,14 (KCLB)

D3S1358 16,17

D5S818 12,13 (ATCC; Cosmic-CLP)

 13 (KCLB)

D7S820 9,12

D13S317 11,14 (ATCC; Cosmic-CLP)

 12,14 (KCLB)

D16S539 9,12

FGA 22

TH01 8,9.3

TPOX 8,10

vWA 14

参考文献

PubMed=31068700; DOI=10.1038/s41586-019-1186-3

 Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.

 Next-generation characterization of the Cancer Cell Line Encyclopedia.

 Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023

 Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E., Schweppe D.K., Jedrychowski M., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.

 Quantitative proteomics of the Cancer Cell Line Encyclopedia.

 Cell 180:387-402.e16(2020)