人黑色素瘤细胞IGR-1
BLUEFBIO™ Product Sheet
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细胞名称 |
人黑色素瘤细胞IGR-1 |
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货物编码 |
BFN6021609 |
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产品规格 |
T25培养瓶x1 |
1.5ml冻存管x2 |
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细胞数量 |
1x10^6 |
1x10^6 |
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保存温度 |
37℃ |
-198℃ |
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运输方式 |
常温保温运输 |
干冰运输 |
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安全等级 |
1 |
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用途限制 |
仅供科研用途 3类 |
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培养体系 |
DMEM高糖培养基（不含丙酮酸钠）+10%FBS+1%三抗 |
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培养温度 |
37℃ |
二氧化碳浓度 |
5% |
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简介 |
人黑色素瘤细胞IGR-1取自42岁男性供体。为黑色素瘤腹股沟淋巴结转移株。 |
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注释 |
Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Doubling time: ~75-100 hours (DSMZ). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. |
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突变信息 |
Mutation; HGNC; 1097; BRAF; Simple; p.Val600Lys (c.1798_1799delGTinsAA); ClinVar=VCV000375941; Zygosity=Heterozygous (PubMed=25056119; CCLE; Cosmic-CLP). Mutation; HGNC; 9801; RAC1; Simple; p.Pro29Ser (c.85C>T); ClinVar=VCV000376362; Zygosity=Heterozygous (PubMed=25056119; CCLE; Cosmic-CLP). |
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STR信息 |
Amelogenin X,Y CSF1PO 10 D3S1358 14,17 D5S818 10,11 (CLS; Cosmic-CLP; DSMZ; PubMed=25877200) 10,14 (PubMed=25056119) D7S820 10,11 D8S1179 10 (CLS) 10,14 (PubMed=25056119; PubMed=25877200) D13S317 13 D16S539 11 (PubMed=25056119) 11,13 (CLS; Cosmic-CLP; DSMZ; PubMed=25877200) D18S51 14,16 (PubMed=25877200) 16 (CLS) D21S11 32.2 FGA 23,24 Penta D 10 Penta E 7,11 TH01 7,9.3 (CLS) 9.3 (Cosmic-CLP; DSMZ; PubMed=25056119; PubMed=25877200) TPOX 8 vWA 17,18 (CLS; Cosmic-CLP; DSMZ; PubMed=25877200) 18 (PubMed=25056119)
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参考文献 |
PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A. An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines. Cancer Res. 79:1263-1273(2019)
PubMed=31068700; DOI=10.1038/s41586-019-1186-3 Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature 569:503-508(2019)
PubMed=31978347; DOI=10.1016/j.cell.2019.12.023 Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E., Schweppe D.K., Jedrychowski M., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P. Quantitative proteomics of the Cancer Cell Line Encyclopedia. Cell 180:387-402.e16(2020)
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