人乳腺导管癌细胞T47D

细胞名称

人乳腺导管癌细胞T47D

货物编码

BFN60805678

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研           1类

培养体系

DMEM高糖+10%FBS+1%双抗

培养温度

37℃

二氧化碳浓度

5%

简介

人乳腺导管癌细胞T47D由IKeydar分离自一位54岁乳房侵入性导管癌的女性患者的胸腔积液；分化的上皮亚株(T-47D)有细胞质连接和17β雌二醇及其他类固醇激素、降钙素的受体；表达WNT7B癌基因。

注释

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Part of: COSMIC cell lines project.

Part of: ENCODE project common cell types; tier 3.

Part of: GrayJW Breast Cancer Cell Line Panel.

Part of: ICBP43 breast cancer cell line panel.

Part of: JFCR45 cancer cell line panel.

Part of: KuDOS 95 cell line panel.

Part of: MD Anderson Cell Lines Project.

Part of: NCI-60 cancer cell line panel.

Part of: NCI-7 clinical proteomics reference material cell line panel.

Doubling time: 1.6 days (PubMed=9671407); 45.5 hours (NCI-DTP); 32 hours (CLS); ~30-40 hours (DSMZ); ~43 hours (PBCF); 55.80 hours (https://www.synapse.org/#!Synapse:syn2347014).

Microsatellite instability: Stable (MSS) (PubMed=12661003; PubMed=23671654; Sanger).

Omics: Array-based CGH.

Omics: CNV analysis.

Omics: Deep exome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: Deep RNAseq analysis.

Omics: DNA methylation analysis.

Omics: Fluorescence phenotype profiling.

Omics: Glycoproteome analysis by proteomics.

Omics: lncRNA expression profiling.

Omics: Metabolome analysis.

Omics: miRNA expression profiling.

Omics: N-glycan profiling.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

Misspelling: T470; In Cosmic 877451 and Cosmic 1152529.

Misspelling: T74D; In Cosmic 1027050.

Misspelling: T-47D-RU; In Cosmic 1175835.

Sequence variations

Heterozygous for PIK3CA p.His1047Arg (c.3140A>G) (PubMed=17088437; PubMed=19593635; PubMed=28889351).

Homozygous for TP53 p.Leu194Phe (c.580C>T) (PubMed=16541312; PubMed=17088437; PubMed=18277095; PubMed=21912889; PubMed=28889351).

STR信息

参考文献