人弥漫大B淋巴瘤细胞TMD8

细胞名称

人弥漫大B淋巴瘤细胞TMD8

货物编码

BFN60806614

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研           2类

培养体系

DMEM高糖+10%FBS+1%双抗

培养温度

37℃

二氧化碳浓度

5%

简介

人弥漫大B淋巴瘤细胞TMD8取自62岁男性供体。

序列突变

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注释

Characteristics: Genetic heterogeneous, consists of 3 subclones (PubMed=27566572).

Doubling time: ~30 hours (PubMed=16780947).

Omics: Deep exome analysis.

Omics: Deep RNAseq analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

Misspelling: TDM8; In PubMed=23292937.

Derived from sampling site: Bone marrow.

STR信息

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参考文献

PubMed=16780947; DOI=10.1016/j.leukres.2006.05.003

Tohda S., Sato T., Kogoshi H., Fu L., Sakano S., Nara N.

Establishment of a novel B-cell lymphoma cell line with suppressed growth by gamma-secretase inhibitors.

Leuk. Res. 30:1385-1390(2006)

PubMed=23292937; DOI=10.1073/pnas.1205299110

Zhang J., Grubor V., Love C.L., Banerjee A., Richards K.L., Mieczkowski P.A., Dunphy C., Choi W., Au W.Y., Srivastava G., Lugar P.L., Rizzieri D.A., Lagoo A.S., Bernal-Mizrachi L., Mann K.P., Flowers C., Naresh K., Evens A., Gordon L.I., Czader M.B., Gill J.I., Hsi E.D., Liu Q., Fan A., Walsh K., Jima D., Smith L.L., Johnson A.J., Byrd J.C., Luftig M.A., Ni T., Zhu J., Chadburn A., Levy S., Dunson D.B., Dave S.S.

Genetic heterogeneity of diffuse large B-cell lymphoma.

Proc. Natl. Acad. Sci. U.S.A. 110:1398-1403(2013)

PubMed=25485619; DOI=10.1038/nbt.3080

Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.

A comprehensive transcriptional portrait of human cancer cell lines.

Nat. Biotechnol. 33:306-312(2015)

PubMed=27566572; DOI=10.18632/oncotarget.11524

Quentmeier H., Pommerenke C., Ammerpohl O., Geffers R., Hauer V., MacLeod R.A.F., Nagel S., Romani J., Rosati E., Rosen A., Uphoff C.C., Zaborski M., Drexler H.G.

Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation.

Oncotarget 7:63456-63465(2016)