人膀胱上皮癌细胞RT112/84

细胞名称

人膀胱上皮癌细胞RT112/84

货物编码

BFN60807659

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研        1类

培养体系

90%DMEM+10%FBS+1%双抗 

培养温度

37℃

二氧化碳浓度

5%

简介

人膀胱上皮癌细胞RT112/84取自欧洲女性，年龄不详。该细胞源于ECACC

注释

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Omics: Deep exome analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

基因突变

FGFR3-TACC3 gene fusion (from parent cell line).

TERT c.228C>T (-124C>T); in promoter (from parent cell line).

Heterozygous for TP53 p.Ser183Ter (c.548C>G) and p.Arg248Gln (c.743G>A) (CCLE).

HLA信息

/

STR信息

Amelogenin        X

CSF1PO        10,11

D5S818        10,13

D7S820        11,12

D13S317        13,14

D16S539        11,13

TH01        7

TPOX        8,11

vWA        14,17

参考文献

PubMed=29732388; DOI=10.3233/BLC-180167

Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.

Systematic review: characteristics and preclinical uses of bladder cancer cell lines.

Bladder Cancer 4:169-183(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747

Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3

Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Nature 569:503-508(2019)