人弥漫大B淋巴瘤细胞OCI-Ly1

细胞名称

人弥漫大B淋巴瘤细胞OCI-Ly1

货物编码

BFN60808875

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研   2类

培养体系

90%DMEM+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人弥漫大B淋巴瘤细胞OCI-Ly1取自44岁男性供体，该细胞源于DSMZ

注释

From: Ontario Cancer Institute (OCI); Toronto; Canada.

Doubling time: ~50-60 hours (DSMZ).

Omics: Array-based CGH.

Omics: CNV analysis.

Omics: Deep exome analysis.

Omics: Deep RNAseq analysis.

Omics: Genome sequenced.

Omics: H3K9ac ChIP-seq epigenome analysis.

Omics: miRNA expression profiling.

Omics: Transcriptome analysis.

Derived from sampling site: Bone marrow.

基因突变

/

HLA信息

Class I

HLA-A        A*02:01

HLA-C        C*05:01,05:01

STR信息

Amelogenin        X,Y

CSF1PO        10,11

D5S818        11,12

D7S820        11

D13S317        12

D16S539        9

TH01        9.3

TPOX        8,9

vWA        15,16

参考文献

PubMed=19358282; DOI=10.1002/ijc.24351

Inagaki A., Ishida T., Yano H., Ishii T., Kusumoto S., Ito A., Ri M., Mori F., Ding J., Komatsu H., Iida S., Ueda R.

Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.

Int. J. Cancer 125:212-221(2009)

PubMed=23292937; DOI=10.1073/pnas.1205299110

Zhang J., Grubor V., Love C.L., Banerjee A., Richards K.L., Mieczkowski P.A., Dunphy C., Choi W., Au W.Y., Srivastava G., Lugar P.L., Rizzieri D.A., Lagoo A.S., Bernal-Mizrachi L., Mann K.P., Flowers C., Naresh K., Evens A., Gordon L.I., Czader M.B., Gill J.I., Hsi E.D., Liu Q., Fan A., Walsh K., Jima D., Smith L.L., Johnson A.J., Byrd J.C., Luftig M.A., Ni T., Zhu J., Chadburn A., Levy S., Dunson D.B., Dave S.S.

Genetic heterogeneity of diffuse large B-cell lymphoma.

Proc. Natl. Acad. Sci. U.S.A. 110:1398-1403(2013)

PubMed=23699601; DOI=10.1182ood-2013-02-483727

Morin R.D., Mungall K., Pleasance E.D., Mungall A.J., Goya R., Huff R.D., Scott D.W., Ding J., Roth A., Chiu R., Corbett R.D., Chan F.C., Mendez-Lago M., Trinh D.L., Bolger-Munro M., Taylor G., Hadj Khodabakhshi A., Ben-Neriah S., Pon J., Meissner B., Woolcock B., Farnoud N., Rogic S., Lim E.L., Johnson N.A., Shah S., Jones S., Steidl C., Holt R., Birol I., Moore R., Connors J.M., Gascoyne R.D., Marra M.A.

Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing.

Blood 122:1256-1265(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893

Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.

OncoImmunology 3:E954893-E954893(2014)