人弥漫大B淋巴瘤细胞OCI-Ly18

细胞名称

人弥漫大B淋巴瘤细胞OCI-Ly18

货物编码

BFN60808878

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研   2类

培养体系

90%DMEM+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人弥漫大B淋巴瘤细胞OCI-Ly18取自56岁男性供体，该细胞源于DSMZ

注释

From: Ontario Cancer Institute (OCI); Toronto; Canada.

Doubling time: ~30-40 hours (DSMZ).

Omics: Array-based CGH.

Omics: CNV analysis.

Omics: miRNA expression profiling.

Omics: Transcriptome analysis.

Misspelling: OCI-LZ18; In BioSample SAMN03473448.

Misspelling: SU-DHL-18; In Cosmic 1295513.

Derived from sampling site: Pleural effusion.

基因突变

/

HLA信息

/

STR信息

Amelogenin        X

CSF1PO        10,12

D5S818        11,12

D7S820        10,12

D13S317        10,12

D16S539        11,13

TH01        6,9

TPOX        8,11

vWA        15,19

参考文献

PubMed=8574164; DOI=10.3109/10428199509059672

Chang H., Blondal J.A., Benchimol S., Minden M.D., Messner H.A.

p53 mutations, c-myc and bcl-2 rearrangements in human non-Hodgkin's lymphoma cell lines.

Leuk. Lymphoma 19:165-171(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5

Drexler H.G.

The leukemia-lymphoma cell line factsbook.

(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=11807979; DOI=10.1002/gcc.10025

Mehra S., Messner H.A., Minden M.D., Chaganti R.S.K.

Molecular cytogenetic characterization of non-Hodgkin lymphoma cell lines.

Genes Chromosomes Cancer 33:225-234(2002)

PubMed=19278952; DOI=10.1182ood-2009-01-202028

Li C., Kim S.-W., Rai D., Bolla A.R., Adhvaryu S., Kinney M.C., Robetorye R.S., Aguiar R.C.T.

Copy number abnormalities, MYC activity, and the genetic fingerprint of normal B cells mechanistically define the microRNA profile of diffuse large B-cell lymphoma.

Blood 113:6681-6690(2009)

PubMed=26727417; DOI=10.3109/10428194.2015.1108414

Drexler H.G., Eberth S., Nagel S., MacLeod R.A.F.

Malignant hematopoietic cell lines: in vitro models for double-hit B-cell lymphomas.

Leuk. Lymphoma 57:1015-1020(2016)