人muller细胞MIO-M1

细胞名称

人muller细胞MIO-M1

货物编码

BFN6021542

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研用途        3类

培养体系

DMEM高糖培养基（不含丙酮酸钠）+10%FBS+1%三抗

培养温度

37℃

二氧化碳浓度

5%

简介

人muller细胞MIO-M1取自女性供体。该细胞为自发永生化细胞系。

注释

Omics: Deep proteome analysis.

Omics: Metabolome analysis.

Derived from sampling site: Eye; retina; Muller glia.

突变信息

STR信息

参考文献

PubMed=11867609

 Limb G.A., Salt T.E., Munro P.M.G., Moss S.E., Khaw P.T.

 In vitro characterization of a spontaneously immortalized human Muller cell line (MIO-M1).

 Invest. Ophthalmol. Vis. Sci. 43:864-869(2002)

PubMed=17525239; DOI=10.1634emcells.2006-0724

 Lawrence J.M., Singhal S., Bhatia B., Keegan D.J., Reh T.A., Luthert P.J., Khaw P.T., Limb G.A.

 MIO-M1 cells and similar Muller glial cell lines derived from adult human retina exhibit neural stem cell characteristics.

 Stem Cells 25:2033-2043(2007)

PubMed=22065927

 Hollborn M., Ulbricht E., Rillich K., Dukic-Stefanovic S., Wurm A., Wagner L., Reichenbach A., Wiedemann P., Limb G.A., Bringmann A., Kohen L.

 The human Muller cell line MIO-M1 expresses opsins.

 Mol. Vis. 17:2738-2750(2011)

PubMed=30176221; DOI=10.1016/j.exer.2018.08.016

 Eastlake K., Heywood W.E., Banerjee P., Bliss E., Mills K., Khaw P.T., Charteris D., Limb G.A.

 Comparative proteomic analysis of normal and gliotic PVR retina and contribution of Muller glia to this profile.

 Exp. Eye Res. 177:197-207(2018)

PubMed=31254428; DOI=10.1111/ceo.13578

 Churm R., Dunseath G.J., Prior S.L., Thomas R.L., Banerjee S., Owens D.R.

 Development and characterization of an in vitro system of the human retina using cultured cell lines.

 Clin. Exp. Ophthalmol. 47:1055-1062(2019)

PubMed=32152301; DOI=10.1038/s41467-020-15066-6

 Singh C., Tran V., McCollum L., Bolok Y., Allan K., Yuan A., Hoppe G., Brunengraber H., Sears J.E.

 Hyperoxia induces glutamine-fuelled anaplerosis in retinal Muller cells.

 Nat. Commun. 11:1277-1277(2020)